Glossary
Dosage titration
Gradual stepwise dose-adjustment to find the minimum effective dose with tolerable side effects.
Titration is the stepwise adjustment of dose to balance efficacy against side effects. In cannabinoid therapy the mantra is "start low, go slow": begin at a low dose (often 2.5 mg THC or 10 mg CBD), increase weekly or bi-weekly based on response, and hold at the lowest dose delivering clinical benefit. This minimises adverse effects — particularly somnolence, dizziness, and cognitive fog — and helps establish a sustainable long-term regimen.
Related terms
- CannabinoidA class of compounds that interact with the endocannabinoid system — includes plant-derived (THC, CBD), synthetic, and endogenous forms.
- THC (Δ⁹-tetrahydrocannabinol)The principal psychoactive cannabinoid in the cannabis plant.
- CBD (cannabidiol)Non-psychoactive cannabinoid with established use in some seizure disorders and emerging use in anxiety.