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Searching across 74 pages — clinical conditions, medical-cannabis glossary, articles, and city telemedicine guides.
Condition · 10
Chronic pain
Medical cannabis evaluation for chronic pain in South Africa. Evidence overview, when to see a doctor, and how the Section 21 pathway works.
/conditions/chronic-pain
Multiple sclerosis spasticity
MS spasticity and medical cannabis in South Africa. Evidence, Section 21 process, and what to bring to an eligibility consultation.
/conditions/ms-spasticity
Treatment-resistant epilepsy
Medical cannabis (CBD-dominant) in treatment-resistant epilepsy in South Africa. Evidence base for Dravet and Lennox-Gastaut, and how Section 21 is assessed.
/conditions/treatment-resistant-epilepsy
Anxiety disorders
Medical cannabis evaluation for generalised anxiety and social anxiety in South Africa. Evidence overview, safety considerations, and the Section 21 pathway.
/conditions/anxiety-disorders
Neuropathic pain
Medical cannabis evaluation for neuropathic pain — diabetic, post-herpetic, chemotherapy-induced — in South Africa. Evidence overview and the Section 21 pathway.
/conditions/neuropathic-pain
Cancer-related symptoms
Cannabinoid therapy for cancer-related pain, nausea, and appetite loss in South Africa. Adjunct to oncology and palliative care — not a cancer therapy. Section 21 pathway explained.
/conditions/cancer-related-symptoms
Fibromyalgia
Medical cannabis evaluation for fibromyalgia in South Africa. Where it sits alongside duloxetine, pregabalin, and graded exercise — and how the Section 21 pathway works.
/conditions/fibromyalgia
Migraine
Medical cannabis evaluation for chronic and refractory migraine in South Africa. Where cannabinoids sit alongside triptans and CGRP inhibitors, and how the Section 21 pathway works.
/conditions/migraine
Inflammatory bowel disease
Medical cannabis evaluation for IBD (Crohn's, ulcerative colitis) in South Africa. Where cannabinoids sit alongside biologics and steroids, and how the Section 21 pathway works.
/conditions/ibd
Rheumatoid arthritis
Medical cannabis evaluation for rheumatoid arthritis in South Africa. Adjunct symptom management alongside DMARDs and biologics. Section 21 pathway explained.
/conditions/rheumatoid-arthritis
Glossary · 5
Section 21
SAHPRA authorisation for access to unregistered medicines — the primary legal pathway for medical cannabis in SA.
/glossary/section-21
Named Patient Application (NPA)
A Section 21 application for a single, identified patient.
/glossary/named-patient-application
Multiple Patient Application (MPA)
A Section 21 application grouping several patients with the same indication and product.
/glossary/multiple-patient-application
ICD-11
The International Classification of Diseases, 11th Revision — the diagnostic-code standard used in Section 21 applications.
/glossary/icd-11
Medicines and Related Substances Act 101 of 1965
The foundational SA statute governing all medicines, scheduling, and the Section 21 unregistered-medicines mechanism.
/glossary/medicines-act-101
Article · 5
SAHPRA Section 21 in 2026 — typical timelines, costs, and what to expect
A practical, current snapshot of what a patient should expect from intake assessment to medication in hand. End-to-end timing, cost breakdown, and what affects each step.
/articles/section-21-2026-timeline
Cannabidiol (CBD) products in South Africa — Schedule 0 vs Section 21 explained
You can buy low-dose CBD over-the-counter in any SA pharmacy under Gazette 43347, but clinically relevant doses require Section 21 access. Here is the regulatory split, why it exists, and what it means for patients.
/articles/cbd-schedule-0-vs-section-21
International travel with Section 21 cannabis prescriptions — what works and what does not
A SAHPRA Section 21 authorisation is South African — it does not extend across borders. Here is what to know about travel within SA, regional travel in southern Africa, and intercontinental travel.
/articles/international-travel-prescription
Medical aid coverage of medical cannabis in SA — what schemes do and do not cover
Most SA medical schemes do not cover Section 21 medication itself. The doctor consultation may be partly claimable. Here is the current landscape and how to confirm with your scheme.
/articles/medical-aid-coverage
Why medical cannabis is not a first-line treatment — and what that means for your application
Cannabinoid therapy is rarely the first answer for any indication. Understanding why — and what "trialled first-line" actually requires — is the difference between an accepted Section 21 application and a declined one.
/articles/not-first-line-treatment
City · 10
Cape Town — Section 21 telemedicine
HPCSA-registered telemedicine for Cape Town residents. SAHPRA Section 21 medical cannabis prescriptions, assessment to delivery in 3–7 days. No clinic visit required.
/cities/cape-town
Johannesburg — Section 21 telemedicine
HPCSA-registered telemedicine for Johannesburg residents. SAHPRA Section 21 medical cannabis prescriptions, end-to-end in 3–7 days. No travel required.
/cities/johannesburg
Pretoria — Section 21 telemedicine
HPCSA-registered telemedicine for Pretoria residents. SAHPRA Section 21 medical cannabis prescriptions, fully online, 3–7 days end-to-end.
/cities/pretoria
Durban — Section 21 telemedicine
HPCSA-registered telemedicine for Durban / eThekwini residents. SAHPRA Section 21 medical cannabis prescriptions, 3–7 days end-to-end, no clinic visit.
/cities/durban
Gqeberha — Section 21 telemedicine
HPCSA-registered telemedicine for Gqeberha / Port Elizabeth residents. SAHPRA Section 21 medical cannabis prescriptions, 3–7 days end-to-end, no clinic visit.
/cities/gqeberha
East London — Section 21 telemedicine
HPCSA-registered telemedicine for East London / Buffalo City residents. SAHPRA Section 21 medical cannabis prescriptions, 3–7 days end-to-end, no clinic visit.
/cities/east-london
Bloemfontein — Section 21 telemedicine
HPCSA-registered telemedicine for Bloemfontein / Mangaung residents. SAHPRA Section 21 medical cannabis prescriptions, 3–7 days end-to-end, no clinic visit.
/cities/bloemfontein
Polokwane — Section 21 telemedicine
HPCSA-registered telemedicine for Polokwane / Limpopo residents. SAHPRA Section 21 medical cannabis prescriptions, 3–7 days end-to-end, no clinic visit.
/cities/polokwane
Mbombela (Nelspruit) — Section 21 telemedicine
HPCSA-registered telemedicine for Mbombela (Nelspruit) / Mpumalanga residents. SAHPRA Section 21 medical cannabis prescriptions, 3–7 days end-to-end, no clinic visit.
/cities/nelspruit
Stellenbosch — Section 21 telemedicine
HPCSA-registered telemedicine for Stellenbosch / Cape Winelands residents. SAHPRA Section 21 medical cannabis prescriptions, 3–7 days end-to-end, no clinic visit.
/cities/stellenbosch